What is apixaban (apixaban)?

Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes mellitus, or symptomatic heart failure.

How do I cope with the side effects of apixaban?

These common side effects of apixaban happen in more than 1 in 100 people. There are things you can do to help cope with them: If youre tired and lack energy, feel like youre short of breath, have noticeable heartbeats (heart palpitations) and paler than usual skin, these can be signs of anaemia. Talk to your doctor, who may arrange a blood test.

Which doses of apixaban are used in the treatment of cirrhosis?

Full dose apixaban (5 mg [bid]) can be used, unless at least two of the following characteristics apply: patient age is 80 years or older, body weight is 60 kg or less, and serum creatinine is 1.5 mg/dL or higher, in which case dose reduction to 2.5 mg bid is indicated.

What is the antidote for apixaban?

Andexanet alfa is an FDA approved antidote for apixaban in people with uncontrolled and life-threatening bleeding events.

What is apixaban and how does it work?

What is apixaban? Apixaban is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation. Apixaban is also used after hip or knee replacement surgery to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism).

Can I stop taking apixaban for a short time?

You may need to stop taking apixaban for a short time. Do not stop taking apixaban unless your doctor tells you to. Stopping suddenly can increase your risk of blood clot or stroke. If you stop taking apixaban for any reason, your doctor may prescribe another medication to prevent blood clots until you start taking apixaban again.

How many mg of apixaban is in Eliquis?

It’s available in two strengths: 2.5 milligrams (mg) and 5 mg. Eliquis contains the active drug apixaban. Is Eliquis a blood thinner? Yes, Eliquis is a blood thinner. It’s also called an anticoagulant.

Can apixaban cause spinal cord damage?

Apixaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:

Is apixaban recommended for patients with cirrhosis of the liver?

Apixaban requires no dose adjustment in patients with CTP A cirrhosis. While no specific recommendation is available for patients with CTP B cirrhosis, Apixaban is not recommended in patients with CTP C according to its approved prescribing guidance [ 60 Eliquis (apixaban), [package insert], Bristol-Myers Squibb, New York, NY, USA.

Can edoxaban be used in patients with CTP a cirrhosis?

While no dose adjustment is necessary for Edoxaban use in patients with CTP A cirrhosis, the drug is not recommended in patients with CTP B and C [ 61 Savaysa (edoxaban), [package insert], Daiichi Sankyo, Tokyo, Japan. ].

What is apixaban used for?

Apixaban only comes as a tablet you take by mouth. Apixaban is used to treat and prevent blood clots such as deep vein thrombosis and pulmonary embolism. It also helps to lower risk of stroke if you have atrial fibrillation without an artificial heart valve. Bleeding risk warning: This drug increases your risk of bleeding.

When should apixaban be taken with CYP3A4 inhibitors?

If taking apixaban dose >2.5 mg BID, decrease dose by 50% if coadministered with strong dual inhibitors of CYP3A4 and P-gp; if currently taking apixaban 2.5 mg PO BID, avoid coadministration with strong dual inhibitors of CYP3A4 and P-gp

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